5-Amino-1MQ

Quinolinium small molecule, sold for laboratory research.

1: size
HPLC: purity, third-party tested

$45per vial

Identity

What 5-Amino-1MQ is

5-Amino-1MQ is a small, lab-made molecule, not a peptide chain of amino acids like most of the compounds on this site, more like a tiny chemical key cut to fit one specific lock. It's built around a ring structure called a quinolinium, with an amine group attached at one spot, which is where the name comes from. It was designed to block a single enzyme inside cells called NNMT, the way a wedge jammed in a gear stops that gear from turning.

5-Amino-1MQ is a quinolinium small molecule. SBz Industries sells it for laboratory research.

Amino acid sequence: Not applicable, small molecule
Compound class: Quinolinium small molecule
Available sizes: 50 mg

Research

What the research has looked at

In plain terms, with a link to every study. The most useful thing to notice is what each study was done in.

Research so far is limited to laboratory work: fat cells grown in dishes and mice fed a high-fat diet until they carried extra body fat. No study we could verify has tested it in people, so everything on record comes from animal and cell-based work done mainly by one research group based in Texas.

mice2018

Researchers tested a family of quinolinium-based molecules, the type that became known as 5-Amino-1MQ, first in fat cells grown in a dish and then in mice fed a high-fat diet until they carried extra body fat. Blocking the NNMT enzyme lowered fat-building activity in the dish and, in the mice, led to lower body weight, smaller fat pads, and lower blood cholesterol, without changing how much the mice ate.

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.
Neelakantan and colleagues, Biochemical Pharmacology

mice2021

A follow-up study in mice that were already carrying a lot of extra weight from a high-fat diet combined an NNMT-blocking molecule with a switch to a lower-calorie diet. The combination led to greater loss of body weight and fat than the diet change alone, and brought measures of liver fat and body composition closer to those of lean, normally-fed mice.

Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice.
Sampson and colleagues, Scientific Reports

Each study links to its record on PubMed, the US National Library of Medicine database. Checked 25 September 2026.

Handling

Mixing and storage

Full handling guide

01
Let it warm up
Give the vial twenty minutes on the bench before opening it, so water does not condense onto the powder.
02
Add bacteriostatic water
Slowly, down the inside wall of the vial, never straight onto the powder.
03
Let it dissolve
Leave it alone until it clears. Do not shake it. Shaking damages the peptide.
04
Refrigerate and use
Once mixed, it breaks down much faster than the dry powder. Keep it cold and dark.

Documentation

Tested before it goes on sale

An independent lab tests every compound we sell. It confirms the compound is what the label says and measures purity by HPLC.

The latest certificate is on the product page, so you can read the result before you order.

See the certificate

More on 5-Amino-1MQ

5-Amino-1MQ product pageSizes, documentation and the latest certificate.5-Amino-1MQ in the compound referenceStructure, origin and molecular target.5-Amino-1MQ vs GlutathioneSide by side.5-Amino-1MQ vs SS-31Side by side.How to read a certificate of analysisThe fields worth checking before an order.Reconstitution and handlingDiluent down the glass, never onto the cake.Bacteriostatic waterShelf life, volumes and what the preservative does.Storage, stability and degradationWhat each condition buys, in weeks and months.

Questions

Common questions about 5-Amino-1MQ

What is 5-Amino-1MQ?

5-Amino-1MQ is a small, lab-made molecule, not a peptide chain of amino acids like most of the compounds on this site, more like a tiny chemical key cut to fit one specific lock. It's built around a ring structure called a quinolinium, with an amine group attached at one spot, which is where the name comes from. It was designed to block a single enzyme inside cells called NNMT, the way a wedge jammed in a gear stops that gear from turning. SBz Industries sells it for laboratory research only.

Has 5-Amino-1MQ been tested in people?

No published human study turned up in a PubMed search. Everything on record so far was done in cultured fat cells or in mice.

What does '1MQ' stand for?

It's short for 1-methylquinolinium, the ring-shaped chemical backbone the molecule is built on. The '5-amino' part refers to an amine group attached at the 5 position of that ring.

How is 5-Amino-1MQ reconstituted?

5-Amino-1MQ ships as a freeze-dried powder. Mix it with bacteriostatic water, added slowly down the inside wall of the vial, and let it dissolve without shaking. The researcher decides the working concentration, not us, and we publish no protocols.

How should 5-Amino-1MQ be stored?

Store as stated on the product page and the certificate of analysis. Vials ship in plain outer packaging with no product name on the outside.

Is 5-Amino-1MQ tested, and can I see the results?

Yes. An independent lab tests every compound: it confirms the compound is what the label says and measures purity by HPLC. The latest certificate is on the product page, and you can read it before you order.

Who is permitted to purchase 5-Amino-1MQ?

Researchers and institutions, 21 or over. By ordering you confirm the material is for laboratory research and will not be used in humans or animals.

Also in cellular and cofactors

Research library

SLU-PP-332 MOTS-cMitochondrial-derived peptide SS-31Synthetic mitochondria-targeting tetrapeptide NAD+Pyridine dinucleotide coenzyme GlutathioneEndogenous tripeptide thiol L-CarnitineQuaternary ammonium compound

Order

5-Amino-1MQ, third-party tested

Every compound is third-party tested, with the certificate on its product page. Every order ships in plain packaging.

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5-Amino-1MQ

What 5-Amino-1MQ is

What the research has looked at

Mixing and storage

Let it warm up

Add bacteriostatic water

Let it dissolve

Refrigerate and use